Although we are genetically 99 per cent the same, differences in our genetic code impact every aspect of our lives: how we look, feel and behave… our DNA is what makes us – Us. Specific to this discussion, our unique code innately impacts our metabolism: how we absorb (digest), transport, and metabolise fats, carbs and proteins for energy, and how we build body tissue or store energy for later use. Emma and Ian discuss the genes that most impact individual ability and preference to use fats or carbs for fuel, and how this knowledge can inform our dietary choices with respect to optimally supporting exercise training, and improving athletic performance.
By revealing their personal ‘nutrigenomics of metabolism’ results, Emma and Ian compare and contrast their own unique macronutrient preferences in the context of sport, and also delve into a few genes that are particularly impactful for metabolism. They also consider the micronutrient and phytonutrition needs of these metabolic pathways, along with strategies to improve the metabolic flexibility of an athlete.
Ultimately, within potentially quite complex subject matter, the goal of this podcast is to join the dots between a deep dive analysis of the genes of metabolism, and the big picture application of this information within the personal perspective of a sports person.
About Emma Beswick
Emma Beswick Bio MBA, BA (Hons), Dip (NatNut) is an experienced nutritional therapist and co-founder of Lifecode Gx – the foremost nutrigenetic testing and training company. Emma lectures widely on the subject of nutrigenomics and is well known and respected for her knowledge and ability to present complex aspects of nutrigenomics in an accessible and clinically relevant way. As a keen runner (and ‘good for age’ marathoner), she has particular, and personal interests in women’s health, sports nutrition and healthy ageing, and attempts to walk (or run) the talk by applying nutrigenomics in practice.
Website: www.lifecodegx.com
Lifecode Gx Metabolics report
Instagram: @lifecodegx
Relevant research links for this podcast
Below are a list of research articles and areas of academic enquiry within the field of the genetics of metabolism, mentioned by Emma and Ian during their interview:
An example of AMPK and ageing research
An example of mTOR viewed as the ‘baddie’ in health
The role of mTOR in age-related diseases – Chrienova et al (2021)
PGC-1 alpha and its role in metabolism and mitochondrial regulation
PGC-1a: a key regulator of energy metabolism – Liang and Ward (2006)
Mitochondrial regulator PGC-1a – Modulating the modulator – Miller et al. (2019)
Glucokinase gene (GCK) and carb metabolism
The potential to personalise dietary macronutrient ratios based on genetics
How peroxisome genetics can affect adaptation to aerobic training
The role of PGC-1 alpha in fatty acid oxidation and insulin sensitivity
